Speaking on his YouTube channel, Maina told Halfman Flex that he has many politician friends but it is the most hectic job.
"I have seen my friends and what they go through. It is the worst job ever. You don't sleep and you are always wondering whether you are being told the truth," he said.
"You have got an idea of what to do but those guys are telling you no. If there is a crisis like the Westgate saga during Uhuru's leadership.
"That was his most trying moment coz you don't prepare for some things but when they happen, the whole country looks at you for answers.
"That is where you are really tested as a leader. I will never vie for any political office. Even MCA."
He told Flex he would also never fundraise for any of his friends who wanted to vie for a political seat.
"If you vie, never come to me for fundraising. I cannot give to political campaigns or pre-wedding or if your child has been called to university in Australia.
"There are universities in Kenya, why are you going to Australia?
"For a pre-wedding, why am I helping you buy a woman I would never have a piece of?"
He said some of his friends who recently joined politics are acting different.
"Politics, you will get the seat and you change. You will ride on my back and then you flip.
"We saw that just the other day, I will not mention names here, coz he is my boy.
"Politics is not for the faint-hearted, you need to be ruthless. You can't be a nice guy and succeed in politics."
In the interview, Maina also talked about the various heads of state he has met and those he regrets never meeting.
"I have met quite a number of heads of state. I never met the late President Moi, and it is one of my greatest regrets," he said.
"I wish I really did because I would have loved to know how his mind works. I never met Moi."
Unfortunately, Maina also says he didn't meet former US President Barrack Obama when he visited Kenya.
He said he had asked Jalang'o to take him since he was the MC in the Kisumu event but "he never picked my call. It's okay, I watched him on TV".
Maina also wished to have met Nelson Mandela, whom he described as an amazing treasure trove of information and lessons.