Prior to the appointment, he served as Lake Basin Development Authority (LBDA) Managing Director.
He will now work with the Interior CS Kithure Kindiki in transforming the security sector.
Their roles include coordinating state functions and overseeing internal security and public administration among others.
Omollo was given the plum job, ostensibly, as an acknowledgement of his support during the Kenya Kwanza campaigns.
He led the delegation that welcomed Ruto to Homa Bay for his maiden visit on October 2, for a fundraiser at the African Inland Church (AIC).
Ruto said he changed his mind about having his contribution handed in by Omollo and instead opted to come in person.
Ruto garnered fewer votes in the region, given its popularity as Azimio la Umoja One Kenya Alliance leader Raila Odinga's stronghold.
The last Luo to hold the position is Hezekiah Oyugi who was the ministry's Permanent Secretary. That happened 31 years ago.
Oyugi served during the late President Daniel Arap Moi's tenure and exited on October 27, 1991.
Omollo was appointed to LBDA by the former East African Community CS Aden Mohamed in 2019.
