ODM's National Executive Council on Thursday adopted the disciplinary committee's recommendation to expel two rebel MPs.
MPs Aisha Jumwa (Malindi) and Suleiman Dori (Msambweni) have been dewhipped from all parliamentary committees with immediate effect.
The verdict on the case of six Homa Bay MCAs was adjourned to a later date after the committee cited a court order restraining it from discussing the matter.
The Raila Odinga-led ODM party had called for a meeting to decide the fate of two MPs and a host of MCAs who have been recommended for expulsion.
The party's disciplinary committee in June last year recommended that Jumwa and Dori be expelled from the outfit for openly declaring support for Deputy President William Ruto's 2022 presidential bid.
The committee also recommended the expulsion of six MCAs from Homa Bay county following acts of violence, unruly behaviour and disobeying party decisions.
They are Dan Were, Evans Marieba, Julius Gaya, Geoffrey Juma, Paul Ongoro and Joshua Nyabola.
Jumwa has defended her support for Ruto's bid saying the handshake gave way for collaboration with Jubilee.
In January, she accused Mombasa Governor Hassan by calling for her expulsion yet he has also met Ruto.