When United hosted Liverpool last October, there was a negative atmosphere after their previous Premier League game ended in a 4-2 defeat at Leicester.
Ten months on and Liverpool's return to Old Trafford will coincide with another demonstration of supporter unhappiness after a heavy 4-0 defeat at Brentford.
The Brentford defeat moved the Manchester United Supporters Trust to release a strong statement at the way the club is being run.
"As we've always said, a fish rots from the head. And the ultimate responsibility for the terrible state of our football club must lie with its owners, the Glazer family," it read.
United have brought in Argentina defender Lisandro Martinez from Ajax in a deal worth up to £57m, Netherlands full-back Tyrell Malacia from Feyenoord for £14.7m and Denmark midfielder Christian Eriksen on a free since finishing sixth in the table last season.
They have also reached an agreement to sign Real Madrid's Brazil midfielder Casemiro in a deal that would be worth about £70m.
But their horrible form from last season has spilled into this with United taking just four points from a possible 24 - one win, one draw and six defeats - since Cristiano Ronaldo scored a hat-trick in a 3-2 win over relegated Norwich on 16 April.
Ten Hag said: "They just have to deliver. That is my obligation and them. When I talk about players, and I want to emphasise, I'm in the same boat as well. When we are not in the right attitude, I'm not as well. We win together, we lose together."
Ronaldo's absence from most of United's pre-season games fuelled speculation over his future after he also missed the club's return to pre-season training at Carrington.
He played the full match against Brentford having started the 2-1 home defeat by Brighton as a substitute
Ronaldo announced in the build-up to the Liverpool match that he will soon reveal "the truth" about his future after reading so many "lies" this summer.
Will the Portugal forward inspire United against the Reds as Ten Hag looks to avoid becoming just the second United manager to lose each of his first three games in charge of the club in all competitions, after John Chapman in 1921?
